Genetics & Developmental Biology Stories
Baltimore, MD— The CRISPR/Cas9 genome editing system can help scientists understand, and possibly improve, how corals respond to the environmental stresses of climate change. Work led by...
Baltimore, MD—Human activity endangers coral health around the world. A new algal threat is taking advantage of coral’s already precarious situation in the Caribbean and making it even...
Baltimore, MD— Recently published work from Carnegie’s Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step...
Baltimore, MD— Recent work led by Carnegie’s Kamena Kostova revealed a new quality control system in the protein production assembly line with possible implications for understanding...
Baltimore, MD— Carnegie’s Department of Embryology welcomes two new Staff Scientists, both of whom specialize in researching the symbiotic relationships between species.
Brittany Belin...
Baltimore, MD—New work led by Carnegie’s Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of...
Baltimore, MD— New work from a team of Carnegie cell, genomic, and developmental biologists solves a longstanding marine science mystery that could aid coral conservation. The researchers...
Baltimore, MD— Carnegie’s Director of Embryology Yixian Zheng is one of 15 scientists awarded a grant from the...
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In mammals, most lipids, such as fatty acids and cholesterol, are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. The goal of the Farber lab is to better understand the cell and...
Approximately half of the gene sequences of human and mouse genomes comes from so-called mobile elements—genes that jump around the genome. Much of this DNA is no longer capable of moving, but is likely “auditioning” perhaps as a regulator of gene function or in homologous...
The Gall laboratory studies all aspects of the cell nucleus, particularly the structure of chromosomes, the transcription and processing of RNA, and the role of bodies inside the cell nucleus, especially the Cajal body (CB) and the histone locus body (HLB).
Much of the work makes use of the giant...
The first step in gene expression is the formation of an RNA copy of its DNA. This step, called transcription, takes place in the cell nucleus. Transcription requires an enzyme called RNA polymerase to catalyze the synthesis of the RNA from the DNA template. This, in addition to other processing...
Allan Spradling is a Howard Hughes Medical Institute Investigator and director emeritus of the Department of Embryology. His laboratory studies the biology of reproduction particularly egg cells, which are able to reset the normally irreversible processes of differentiation and aging that govern...
Phillip Cleves’ Ph.D. research was on determining the genetic changes that drive morphological evolution. He used the emerging model organism, the stickleback fish, to map genetic changes that control skeletal evolution. Using new genetic mapping and reverse genetic tools developed during his...
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Washington, D.C.— Zehra Nizami has been a graduate student and postdoc in Joe Gall’s lab at the Department of Embryology. She is the fourth recipient of the Postdoctoral Innovation and Excellence (...
Baltimore, MD— The ability of embryonic stem cells to differentiate into different types of cells with different functions is regulated and maintained by a complex series of chemical interactions,...
Baltimore, MD---Athletes, the elderly and those with degenerative muscle disease would all benefit from accelerated muscle repair. When skeletal muscles, those connected to the bone, are injured,...
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